Mycobacterial GenecuvAIs Required for Optimal Nutrient Utilization and Virulence
نویسندگان
چکیده
منابع مشابه
Mycobacterial gene cuvA is required for optimal nutrient utilization and virulence.
To persist and cause disease in the host, Mycobacterium tuberculosis must adapt to its environment during infection. Adaptations include changes in nutrient utilization and alterations in growth rate. M. tuberculosis Rv1422 is a conserved gene of unknown function that was found in a genetic screen to interact with the mce4 cholesterol uptake locus. The Rv1422 protein is phosphorylated by the M....
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15 صفحه اولMannose metabolism is required for mycobacterial growth.
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We investigated the role of the 58-kDa FTT0918 protein in the iron metabolism of Francisella tularensis. The phenotypes of SCHU S4, a prototypic strain of F. tularensis subsp. tularensis, and the Delta FTT0918 and Delta fslA isogenic mutants were analyzed. The gene product missing in the Delta fslA mutant is responsible for synthesis of a siderophore. When grown in broth with various iron conce...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2014
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.02207-14